VIB Nucleomics Core

The VIB Nucleomics Core offers personalized expert services in the fields of expression analysis, miRNA analysis and RNA and DNA sequencing to the life science community (VIB, other academic institutions and industry). Technologies offered are BioNano genome optical mapping, Nanostring nCounter technology, and Next Generation Sequencing (Illumina).

Services

 

Transcriptomics

VIB Nucleomics Core offers gene expression analysis and miRNA analysis using the Nanostring nCounter®. Massive Parallel Sequencing tools are used for RNASeq and smallRNASeq.

Genomics

For genomic analysis, we offer whole genome sequencing and capture-based sequencing (exome, ChIPseq, targeted resequencing) using our Massive Parallel Sequencing instrument portfolio. Nanostring nCounter® CodeSets are used for putative CNV region screening, and genome mapping can be done by making use of our expertise with the BioNano Genomics Irys platform.

Amplicon-based sequencing

This workflow is used for custom sequencing assays, targeted resequencing, and metagenomic 16S rRNA profiling.

Bioinformatics

VIB Nucleomics Core offers solutions to map and quantify genomes and transcriptomes that explain phenotypes of interest. With bioinformatics support as an integral part of our service, the solutions truly range from sample to science. You are not left behind with raw data files after lab experimentation. Our bioinformatics team can guide you through the complex data analysis process and connect you back to your original research question with new scientific insights. Besides regular data quality assessment, data preprocessing, and mapping, our team has many years of experience in comparative analysis, functional analysis, predictive modeling, and assembly & NGS scaffolding for genome finishing purposes.

Portal for Outsourcing

Through its Core4Life network, the VIB Nucleomics Core can give his clients access to other innovative genomics/transcriptomics tools which are not available in-house, including but not limited to Illumina HiSeq2500, HiSeq4000, PacBio RSII.

Resources

 

Probe-based technology

nanostring technologies1For gene expression quantification, we use NanoString nCounter®, a system based on direct multiplexed measurement of gene expression

Next Gen Sequencing

illumina miseq nextseqNext Generation Sequencing platforms, for small and large scale projects: Illumina MiSeq and Illumina NextSeq500

Genome Mapping

BionanogenomicsFingerprints of large DNA molecules are obtained using our in-house Optical Genome mapping technology (BioNano Genomics’ Irys system)

Team

NC consists of the following members:

Contact 

NC locationAddress

VIB Nucleomics Core
O&N4 – Herestraat 49 – Box 816
Room 404-24 / 08.428
3000 Leuven - Belgium

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Tel: +32 (0)16 37 31 28

Route description

By car

E40: Between the exits 22 and 23 of the E40, you take the E314.

E314: You leave the E314 at the exit 16 (diensten, UZ). At the end of the exit, you turn right when coming from the direction of Brussels, or turn left when coming from the other direction. You drive past the fire station and then turn left. Follow the signs “ Onderwijs en Navorsing”. Follow the sign to to parking “ Villa”. Follow the path to building “Onderwijs en Navorsing 1”. Follow this path and cross the street at the markings. Go up the stairs and enter the O&N1 building. From the main entrance, walk in the direction of the library and walk alongside the library. From there, follow the signs listing “Toegang Onderwijs & Navorsing 4″. When you enter the O&N4 building, walk straight ahead until you reach the main entrance hall. From there, take the elevators (no. 04.206) to the 8th floor. When you exit the elevator, turn right and follow the signs listing “VIB Nucleomics Core, 08.428″. If you are unable to find a parking space on Parking Villa, it is best to park you car at the visitors parking place of the hospital. From there, follow the same direction as described for visitors coming by bus or train.

By public transport

The railway station of Leuven is situated at approximately 4 km of the hospital (Gasthuisberg). There is a bus from the railway station to the hospital every 10 minutes. Take one of the busses on platform 2 with the direction “Gasthuisberg”, or take the “Ring-bus” with number 600 on platform 12. The bus stop is situated at the main entrance of the hospital. Once in the hospital, follow the bordeaux arrows. At the end of the way (please note that this is a 5 – 10 minute walk), you will see the elevators. Take the elevator up to the 4th floor. When you exit the elevator, turn left and follow the signs listing “Toegang Onderwijs & Navorsing 4″. When you enter the O&N4 building, walk straight ahead until you reach the main entrance hall. From there, take the elevators (no. 04.206) to the 8th floor. When you exit the elevator, turn right and follow the signs listing “VIB Nucleomics Core, 08.428″.

Here you find more information on itineraries of trains and buses (only in Dutch).